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Hermine H. Maes

Associate Professor
Department of Human and Molecular Genetics, Psychiatry & Massey Cancer Center

Tel: 804 828 8145
Fax: 804 828 8801
Email:
hmaes@vcu.edu
P.O. Box:
980003
VIPBG
Biotech 1-148

My research is mostly focused on understanding the etiology and trajectories of tobacco use and abuse using meta-analyses of adolescent tobacco use data, as well as heterogeneity, developmental, survival and twin-parent analyses that allow better separation of genetic and environmental transmission. As part of the GEDI project, my research involves harmonizing substance use phenotypes across studies and modeling developmental trajectories of substance use and abuse to study the combined effects of genes and environment (GE correlation and interaction). My research also involves psychometric analyses of substance (ab)use phenotypes including tests of measurement invariance across groups, characterization of the biological and genetic basis for vulnerability to tobacco addiction by including measured environments and genotypes into statistical models, and extension of twin pedigree models to be applied to the Swedish population databases. I am part of the Open Mx team and translate existing Mx code into the newly developed R-OpenMx code, that will allow even greater flexibility in specifying statistical (genetic) models, and write documentation for and provide training in the new OpenMx code for structural equation modeling of a range of applications to genetically informative data.

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