Viriginia Institute for Psychiatric and Behavioral Genetics
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Viriginia Institute for Psychiatric and Behavioral Genetics
| Graduate Courses |
Topics for Fall 2004 (Fridays from 9am to 12pm in the VIPBG Conference
Room (Biotech I), except for the first session which will be on Tuesday
October 19 from 2pm to 5pm in the same location.
Text: Methodology for Genetic Studies of Twins and Families by Neale & Cardon
Manual: Mx: Statistical Modeling by Neale, Boker, Xie & Maes, PDF of Mx manual
| Date | Lecture Topic | Lecturer
| 10/19
| Causes of variation/ Biometrical Genetics
| Path analysis/ Matrix algebra Neale | Maes 10/22
| Introduction to Mx (Graphical Interface)
| Fitting saturated models Maes
| 10/29
| Maximum likelihood / Goodness-of-fit Statistics
| Fitting univariate models Neale | Maes 11/5
| Multifactorial threshold model / Ascertainment
| Fitting models to categorical data Neale | Maes 11/12
| Gene x age/sex/environment interaction
| Testing for heterogeneity across sex/age Maes
| 11/19
| Genetic models for correlated data
| Phenotypic factor analysis / Fitting bivariate models Maes
| 12/3
| Independent and common pathway models
| Fitting multivariate models Maes
| 12/10
| Developmental continuity and change OR Extended Pedigrees
| Fitting models to longitudinal data or extended pedigrees Maes
| 12/17
| Issues in study design & power
| Power Calculations & Simulation Neale
| 1/9
| Methods for identifying QTL's
| QTL analysis Neale
| 1/16
| Linkage and Association
| Models for linkage and assocation Neale
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