VCU Home Virginia Institute for Psychiatric and Behavioral Genetics Seminars

VIPBG Seminars

Seminars are held each Thursday from 12 to 1pm in the VIPBG conference room (Biotech 1-160). If you are interested in being contacted about upcoming seminars, please e-mail Jack Hettema at jhettema@vcu.edu

Previous seminar titles can be viewed below. To see some select slides from previous seminars, click here.

See below for the schedule of upcoming 2007-2008 seminars:

VIPBG Seminars 2007-2008

9/27Paul Andrews, Postdoctoral Fellow Evolution and epistemology in mental health science: Distinguishing defense mechanisms from mental disorders
10/25Hermine Maes, Associate ProfessorCross-cultural comparison of genetic and environmental transmission of smoking initiation using an extended twin kinship model
11/8 Mark Reimers, Assistant ProfessorStatistical methods for pathway-based investigations of disease in genotype and gene expression studies
11/15Thomas Kubarych, Research AssociateNarcissism, Self-Deception, Conscience and Evil
11/22No SeminarN/A
11/29Qi Chen, Postdoctoral FellowAssociation and expression study of CSF2RB gene with schizophrenia
12/6 Brion Maher, Assistant ProfessorLarge scale candidate gene association studies of drug use disorder and ADHD
12/13Michael Neale, ProfessorSome Issues in GxE, Comorbidity & Factor Analysis
12/20No SeminarN/A
1/3 Yuan Gao, Assistant ProfessorIlluminating the Genome Landscape by Deep Sequencing
1/10OPEN
1/17Elizabeth Prom-Wormley, Postdoctoral FellowThe Effects of Genes and Environment on Diurnal Levels of Cortisol, Testosterone and DHEA
1/24Steve Aggen, Research AssociateThe Scaling of Behavioral and Psychological Symptoms: Assessing Differential Moderation of the DSM-IV Criteria for Borderline Personality Disorder
1/31Nathan Gillespie, Postdoctoral FellowThe role of peer group deviance and drug availability in the genetic and environmental pathways to cannabis use, abuse and dependence
2/7 Jack Hettema, Associate, ProfessorTesting genes under a mouse anxiety QTL region for association in human internalizing disorders
2/14Steve Negus, ProfessorSome Determinants of Drug Choice in Rhesus Monkeys: Implications for the Genetics of Drug Abuse
2/21Brien Riley, Assistant ProfessorGSK-3B, Wnt signaling, and DKK2 in alcohol depenedence
2/28Vladimir Vladimirov, Assistant ProfessorIdentification of a novel miRNA gene in dysbindin
3/6 Mark Reimers, Assistant ProfessorFurther excursions in pathway analysis for psychiatric genetics
3/13Darlene Brunzell, Assistant ProfessorGenes, proteins, and behavior; elucidating mechanisms of nicotine addiction
3/20Mats Forsman, Doctoral Student(Karolinska Institute) Genetic and Environmental Influences on Psychopathic Personality in Adolescence
3/27Anyuan Guo, Postdoctoral FellowDystrobrevin binding protein 1 (DTNBP1) gene features analysis
4/3 Zhongming Zhao, Assistant ProfessorCandidate genes for schizophrenia: a survey of association studies and gene ranking
4/10Danielle Dick, Assistant ProfessorCharacterizing the Risk associated with Genes Influencing Alcohol Dependence
4/17Alexis Edwards, Doctoral Student (NCSU)The Genomics of Aggressive Behavior in Drosophila melanogaster
4/24Cancelled
5/1 Kenneth Kendler, Distinguished Professor Empirical Tests of Psychiatric Nosology -- Uncomplicated Bereavement, 'Normal' Sadness, and Major Depression
5/8 Jingchun Sun, Postdoctoral FellowDysbindin: protein interactions and networks
5/15Fazil Aliev, Postdoctoral FellowMultiple testing problems in linkage and association studies
5/22Charles Gardner, Research AssociateThe Dynamic Inter-relationship of Major Depression and Coronary Artery Disease: Attempts at Statistical Modeling
5/29Seon-Sook An, Research AssociateA study of NPY receptor genes: genotyping discrepancy and potential Copy Number Variations using pyrosequencing
6/5 CANCELLED
6/12Darlene Kertes, Postdoctoral FellowHypothalamic-pituitary-adrenocortical axis genes in comorbid alcohol dependence and major depression
6/19Gursharan Kalsi, Research AssociateTBA
6/26

VIPBG Seminars 2006-2007

9/14Seth RobertsPredicting Gene Essentiality: The Gene Takeout Method
9/21Bradley Todd Webb, Research AssociateData Integration and Gene Prioritization Lead to Schizophrenia Pharmacongenetic Discover
9/28Jack Hettema, Assistant ProfessorTesting the Association Between the COMT Gene and Susceptibility to Anxiety-Spectrum Disorders
10/5Michael Miles, ProfessorIdentification of Genetic Loci Linked to Acute Ethanol Responsive Gene Expression in Prefrontal Cortex
10/12Richard Kennedy, Graduate AssistantProbe-level Analysis of Microarray Data
10/19Hermine Maes, Assistant ProfessorTBA
10/26No SeminarN/A
11/2James Eric Schmitt, Graduate StudentA Different Kind of Fine Mapping: High-Resolution Family Studies of Pediatric Brain Morphology
11/16Sarah Medland, Postdoctoral FellowResults from Linkage and Drug behaviours projects
11/30Brion Maher, Assistant ProfessorInitial Discovery and Replication in Large Scale Genetic Association Studies: A Sequential Analysis Approach
12/07Brien P. Riley, Assistant ProfessorThe emerging importance of copy number variation in the human genome
12/14Timothy York, Assistant ProfessorThe use of Finite Mixture Models to Handle Drug Response Heterogeneity in Pharmacogenetic Studies
1/11Sam Chen, Assistant ProfessorAre there common genetic factors in nicotine dependence and other substance use/abuse?
1/25Charles Gardner, Research AssociateTBA
2/1Gursharan Kalsi, Postdoctoral FellowAlcohol, glutamate receptors and beyond
2/15Paul Andrews, Postdoctoral FellowWhen truth is not told: A method for testing the effects of underreporting and applying it to gender differences in perceptions of sexual infidelity and heritability estimates of drug abuse
2/22Brien P. Riley, Assistant ProfessorIdentifying Novel Candidate Genes from DNA-pooled Whole Genome Association (or Damn, that's cheap! Does it work?)
3/1Michael Neale, PhD - ProfessorThe measurement and analysis of complex traits
3/8Mark Reimers, Assistant ProfessorSome statistical methods for gene groups in expression data and some new directions
3/15Matthew Keller, Postdoctoral FellowPedSim: A general simulator of pedigree data and evolutionary processes
3/22Nathan Gillespie, Postdoctoral FellowTBA
3/29Po-Hsiu Kuo, Research AssociateApplications of Finite Mixture models- is it just another fancy model?!
4/5Zhongming Zhao, Assistant ProfessorCpG Islands and DNA Methylation: Does Methylomics Approach Work in Psychiatry?
4/12Cizhong Jiang, Postdoctoral FellowEvidence and Model of Loss of promoter-associated CpG islands in mammals
4/19Kenneth Kendler, Co-director and Distinguished ProfessorDevelopmental Models of Externalizing and Anxiety Disorders
4/26Steven Aggen, Research AssociateMeasuring the Mind: A Discussion of Current Topics in Psychometrics
5/3Tom Kubarych, Research AssociateStem-probe, ordinal data and clinical significance issues in measurement non-invariance studies: examples from DSM-IV Generalized Anxiety and Narcissistic Personality Disorders
5/10Elizabeth Prom, Graduate StudentTBA
5/17Jingchun Sun (Sunny), Postdoctoral FellowGenetic network analysis of schizophrenia-associated genes: preliminary results and future direction
5/24Seon-Sook An, Postdoctoral FellowCREB1 Gene Association Study with Major Depressive Disorder and Anxiety Disorders
5/31Edwin van den Oord, Associate ProfessorThe center for biomarker research and personalized medicine
6/7Joseph McClay, Associate ProfessorTBA
6/14Daniel Adkins, Postdoctoral FellowTBA
6/21Dawn Thiselton, Postdoctoral FellowTBA
6/28Vladimir Vladimirov, Assistant ProfessorTBA

VIPBG Seminars 2005-2006

9/08Visting Professor, Dr. Robert Kimberly"Hard problems" seminar on lupus genetics
9/15No SeminarN/A
9/22Bradley Todd Webb, Postdoctoral FellowSystematic selection of candidate genes by model-based data integration.
9/29Lan Zhang, Postdoctoral FellowSearching for the genes associated with smoking
10/06Jack Hettema, Assistant ProfessorAssociation Between Glutamic Acid Decarboxylase (GAD) Genes and Mood and Anxiety Disorders
10/13No SeminarN/A
10/20Charles Gardner, Research AssociateApplications of generalized linear mixed models to twin data.
10/27Noon: Nathan Gillespie, Postdoctoral Fellow
2PM: Michael Grotewiel, Professor
Noon: Modeling of Measures of Drug Availability: Alcohol, Cigarettes, Marijuana & Cocaine.
2PM: Questions and Approaches to Studying Drosophila Behavior
11/03Xiangning "Sam" Chen, Assistant Professor>Search for schizophrenia genes in 5q an update
11/10Jaime Robles, Research AssociateModel Discovery using Artificial Intelligence
11/17Special Guest, Philosopher Dr. Dominic MurphyTBA
11/24No SeminarHoliday
12/01Vladimir Vladimirov, Postdoctoral FellowA Region of 35kb Containing the Trace Amine Associated Receptor 6 (TAAR6) Gene is Associated with Schizophrenia in the Irish Study of High Density Schizophrenia Families.
12/08Timothy Bates, Guest SpeakerLinkage for dyslexia in a normal sample
12/15Thomas Kubarych, Research AssociateMI2: Investigating Measurement Invariance of Generalized Anxiety Disorder Symptoms in the Virginia Twin Registry and National Comorbidity Survey
12/22No SeminarHoliday
12/29No Seminar Holiday
1/05Paul Andrews, Postdoctoral FellowDepression and problem-solving: History and development of an idea
1/12Brien Riley, Assistant ProfessorAlcohol dependence is associated with the ZNF699 gene, the human ortholog of Drosophila hangover/CG32575
1/19Kelly Tracy, Graduate StudentGenetic and Environmental Factors Contributing to the Development of Antisocial Behavior in Male and Female Young Adults
1/26Cristina Vargas-Irwin, Postdoctoral FellowBehavioral economic aspects of addiction
2/02Jozsef Bukzsar, Postdoctoral FellowEstimating the proportion of true null hypotheses and average effect size in large scale genetic case-control studies
2/08Timothy Newman, Faculty CandidateFunctional Candidate Gene Studies and the Evolution of Behavior in Primates: Lessons from the MAOA Gene
2/09Kristopher Preacher, Faculty CandidateAssessing mediation, moderation, and conditional indirect effects
2/16Matthew Keller, Postdoctoral FellowResolving the Paradox of Common, Harmful, Heritable Mental Disorders: Which Evolutionary Genetic Models Work Best?
2/23James Eric Schmitt, Graduate StudentDetecting latent normality with ordered latent class models
3/02Cizhong Jiang, Postdoctoral FellowAnalysis of Mutational Spectrum in Categorized Human Genomic Regions
3/09Steven Aggen, Research AssociateLatent Psychiatric Phenotypes:Establishing a Basis for Informative Comparisons Applications to DSM Major Depressive & Borderline Personality Disorder Criteria
3/16Guest Speaker Geoff MillerA general fitness factor underlying cognitive function, mental health and physical health: Theory and evidence from 12,749 Vietnam-era veterans
3/23Dawn Thiselton, Postdoctoral FellowMolecular genetic studies of candidate susceptibility genes for schizophrenia
3/30Po-Hsiu Kuo, Research AssociateThe temporal relationship of the onsets of alcohol dependence and major depression
4/06Zhongming Zhao, Assistant ProfessorNucleotide Variation and Haplotype Diversity in a 10-kb Noncoding Region in Three Continental Human Populations
4/13Gursharan Kalsi, Postdoctoral FellowFine-mapping the Alcohol Dependence Susceptibility Locus on 4q22-32 using Tag SNPs
4/20Joseph McClay, Postdoctoral FellowGenotype - environment interactions in metabolic phenotypes
4/27Michael Neale, PHD - ProfessorThoughts about the future of Mx
5/04Carla Mazefsky, Postdoctoral FellowAutism: Introduction to the Phenotype and Research Examples
5/11Edwin van den Oord, Associate ProfessorNew tools for analyzing genome-wide association data and designing subsequent replication studies.
5/18Lindon Eaves, Co-director and Distinguished ProfessorSome Things I Worry About
5/25Donna Miles, Assistant ProfessorVirginia Youth Tobacco Project: Preliminary Findings.
6/01Kenneth Kendler, Co-director and Distinguished ProfessorThe Role of Theory in Psychiatric Research: A review of the Dopamine Hypothesis of Schizophrenia
6/08OPENOPEN
6/15OPENOPEN
6/22OPENOPEN
6/29Elizabeth Prom, Graduate StudentUse of Monoamine Oxidase-A, Serotonin Transporter Promoter, and Dopamine Transporter Polymorphisms as Common Genetic Risk Factors for Adolescent Conduct Disorder and Hyperactivity

VIPBG Seminars 2004-2005

1/06Paul Andrews, Postdoctoral FellowAnalytical Reasoning and Depression
1/13Lindon Eaves, Distinguished Professor and DirectorThe Mating Game
1/20Charles Gardner, Research AssociateClustered, Confounded, and Confused: Opportunities and Dangers with Clustered Observational Data
1/27Cristina Vargas-Irwin, Postdoctoral FellowBehavioral and genetic markers of drug addiction in an adolescent murine model
2/03Hermine Maes, Assistant ProfessorSmoking: An extended/reduced 'extended twin kinship' analysis
2/10Kenneth Kendler, Professor and DirectorReduction, Emergence and Explanatory Pluralism
2/17No seminarN/A
2/24Nathan Gillespie, Postdoctoral FellowFactor and Item-Response Analysis of DSM-IV Criteria for Abuse of and Dependence on Cannabis, Cocaine, Hallucinogens, Sedatives, Stimulants and Opiates
3/03Dr. Clyde FrancksParent-of-origin effects on handedness and schizophrenia on 2p12-q11
3/07 Special SeminarDr. Robin Murray, Visiting ScholarEnvironmental Causes of Schizophrenia
3/10Steve Aggen, Research AssociateLatent Variables: A Look at Their Place in Behavioral Sciences Research
3/10 Special SeminarFred Wolf, Faculty CandidateInterview with a Fly: Neural and MolecularSubstrates for Drosophila Locomotor Behavior
3/15 Special SeminarDr. Isaac Marks, Visiting ScholarWhat Leads to Normal and Morbid Fear and Anxiety?
3/16 Special SeminarSarah Medland, Postdoctoral CandidateThe genetics of handedness: Results from a large international colaborative study
3/17 Special SeminarJustin Rhodes, Ph.D., Faculty CandidateNeural Circuits underlying motivation for natural and drug rewards
3/17Joseph McClay, Postdoctoral FellowVariance component analysis of polymorphic metabolic network
3/23 Special SeminarDarlene Kertes, Postdoctoral CandidateEffects of early life experience on adrenocortical function
4/07Zhongming Zhao, Assistant ProfessorSequence-Context Analysis of Single Nucleotide Polymorphisms
4/14No SeminarN/A
4/21Mike Neale, Steven Aggen, and Tom KubarychJournal Article Discussion
4/28No SeminarN/A
5/12Brien P. Riley, Assistant ProfessorBeyond Positional Cloning and Association: the search for causal variation in DTNBP1
5/19Elizabeth Prom, Graduate StudentThe Roles of Monoamine Oxidase-A and Childhood Adversity as Risk Factors for Conduct Disorder in Females
5/26Charles Anderson, Postdoctoral FellowTBA
6/02James Eric Schmitt, Graduate StudentHeritability of brain volumes in a genetically informative pediatric sample
6/03 Special SeminarTara Turley, Postdoctoral CandidateUse of Covariates in the Linkage Analysis of Complex Qualitative Traits
6/09 NoonPo-Hsiu Kuo, Postdoctoral FellowTBA
6/09 2PMCarla Mazefsky, Postdoctoral CandidateAutism Spectrum Diagnostic Research: Past Studies and Future Directions
6/16 Guest SpeakerDr. David ReissGene-environment interaction and preventive intervention: is this couple ready for marriage?
6/23Robin Page Goin, Postdoctoral FellowCo-occurrence of Asthma and Externalizing Symptoms Among Children and Adolescents
7/07 Guest Speaker Linda HancockTylenol, Twinkies and Genetic Snowflakes: Translating basic science knowledge for teenager consumption.

VIPBG Research Seminars 2003-2004

09/30Jack Hettema, Assistant ProfessorThe Relationship Between Neuroticism and Internalizing Disorders
10/07Carol Prescott, Associate ProfessorInteractions between stressful life events and the serotonin transporter in the prediction of depressive episodes
10/14No SeminarN/A
10/21Jonathan Kuhn, Research AssociateUneven sensitivity when testing gene/environment interaction: a simulation study
10/28Sam Chen, Assistant ProfessorSearching for schizophrenia genes on chromosome 5
11/04Robert Krueger (guest speaker) Associate Professor, University of MinnesotaComparing dimensional and categorical representations of psychpathology
11/11Fengkai Zhang, Postdoctoral FellowBioinformatics Topic: The Use of Vector Seeds to Improve PSI-BLAST Sensitivity
11/18Jozsef Bukszar, Postdoctoral FellowPower calculations for 2 by m tables in one and two stage unmatched case-control designs
11/25No seminarThanksgiving Day
12/0212 PM: Edwin van den Oord, Associate Professor and JR Robles, Research Associate
1 PM: Brian Flaherty, Applicant
12 PM: Multistage LD studies and their computer implementation
1 PM: Using Associative Latent Transition Analysis to Examine Linked Processes
12/09Mike Neale, ProfessorDiscriminating between latent traits and latent classes
12/16Kristen Jacobson, Assistant ProfessorThe structure of antisocial behavior: Results from a genetic factor analysis
12/23No SeminarWinter Closing
12/30No SeminarWinter Closing

VIPBG Research Seminars 2003-2004

9/11/03Jack Hettema, Assistant ProfessorGenetic and Environmental Sources of Covariation Between Generalized Anxiety Disorder and Neuroticism
9/25/03Mike Neale, ProfessorIssues with IRT models and missing data
10/23/03Yongqiang Tang, Postdoctoral CandidateCancer classification using gene expression data
10/30/03Tieband Wang, Postdoctoral CandidateThe sensitivity of Magnaporthe grisea to fenhexamid is determined by a putative GDP/GTP exchange factor (GEF) for Rho1
11/6/03Yihua Che, Postdoctoral FellowA Multiplexing SNP Detection Method Based on Restriction Enzyme Mediated Single Base Extension (REM-SBE)
11/3/03Lindon Eaves, Distinguished ProfessorStruggling to make sense of the environment in behavioral development
11/20/03Brien Riley, Assistant ProfessorA Complete Map of Sequence Variation in the DTNBP1 High-risk Haplotype From The Irish Study Of High Density Schizophrenia Families
11/27/03Brian FlahertyMeasurement structure of the nicotine dependence syndrome scale in the 2001 National Household Survey of Drug Abuse
12/11/03Charles Gardner, Research AssociateA Survey of Methods for Regression Models with Clustered Data
1/8/04Gitta LubkeFactor mixture models applied to ADHD data
1/15/04Hermine Maes, Assistant ProfessorGenetic and environmental transmission of retrospective conduct disorder
1/22/04RObin Page Goin, Postdoctoral FellowAffective disorders in parents of children with autism: Are there implications for different types of autism onset?
1/29/04Dawn Thiselton, Postdoctoral FellowSearching for schizophrenia susceptibility variants on chromosome 8p: no evidence for linkage or association of neuregulin-1 (NRG1) with disease in the Irish Study of High Density Schizophrenia Families (ISHDSF).
2/5/04Carol Prescott, Associate ProfessorEstimating heritability under conditions of unknown zygosity and biased ascertainment: An application using psychiatric diagnoses in the Swedish Twin Registry
2/12/04Matthew Keller, Postdoctoral CandidateAn evolutionary framework for understanding mental disorders: what evolutionary genetics can tell us
2/19/04Paul Andrews, Postdoctoral CandidateDefects in the defect models of depression
3/4/04Tim York, Postdoctoral CandidateGenome-wide variation in human gene expression
3/11/04Zhongming Zhao, Assistant ProfessorSingle Nucleotide Polymorphisms (SNPs) in the Mouse Genome
3/18/04Kevin BolinskyTwins, Personality, and Stressful Life Events
3/25/04Edwin van den Oord, Associate ProfessorThe analysis of large scale genetic data
4/1/04Lindon Eaves, Distinguished ProfessorDeveloping an attitude: election-year behavior genetics
4/8/04Mike Neale, ProfessorMeasurement and gender in latent trait analyses: theory and applications
4/22/04Joseph McClay, Postdoctoral FellowVariance components in biochemical networks with and without competitive inhibition
5/6/04Steven Aggen, Research AssociateGender Differences in MD Prevalence: Measurement Invariance Models for Examining Risk Equivalence
5/13/04Arpana Agrawal, Graduate StudentTesting competition effects in sources of caffeine use: Coffee, soda and tea use in female twins
5/20/04Po-Hsiu Kuo, Postdoctoral CandidateStudies in substance use: Results from genetic and longitudinal studies
5/27/04Elizabeth Prom, Research AssistantX-Inactivation in Females and MAO-A: An Overview
6/10/04Debra Foley, Assistant ProfessorProximal psychiatric risk factors for suicidality in youth aged 9-16 years
6/15/04Tom KubarychPersonality and Psychopathology: Measurement, Models and Classification
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VIPBG Research Seminars 2002-2003

04/24/03Todd WebbDissection of schizophrenia linkages using the DTNBP1 high-risk haplotype
04/04/03Kenneth SchaffnerMolecular and Quantitative Behavioral Genetics: What Kind of a Bridge(s)? (Guest Speaker)
03/27/03Bill Arend/G. MoxleyCytokine Biology / Quantitative genetic aspects of immunity (Guest Speaker)
03/20/03Ayman FanousSuicidal Ideation and its Prediction Using Epidemiological Methods
03/06/03Ken KendlerFirst thoughts on a conceptual framework for psychiatric genetics
02/20/03Robin GoinParental Reports of the Development of Autism in their Children: How do Regression, Comorbidity, and Genetics Fit Into the Picture? (Post Doc Candidate)
01/30/03Arpana AgrawalUse and Abuse/Dependence of Cannabis And Other Illicit Drugs: Examination of the Neale-Kendler Models of Comorbidity
01/16/03Douglas LevinsonGenome scan meta-analysis of schizophrenia and bipolar disorders: simulation and power analysis studies refine the interpretation of results (Guest Speaker)
12/19/02Zhongming ZhaoData Mining Single Nucleotide Polymorphisms (SNPs) in the Human Genome (Bioinformatics Faculty Candidate)
12/17/02Brian FlahertyAssessing the four-class structure of parenting style with an extended latent class model (Research Associate Candidate)
12/12/02Hermine MaesGenetic analyses of smoking initiation, regular smoking and nicotine dependence
12/03/02Timothy Paul YorkComplex trait analysis using modern exploratory methods
12/02/02Karen DavisGenetic Analysis of Keloids
11/21/02Rosemary KelsoDo's & Don'ts of IRB Submissions
11/14/02Paul T. Costa, Jr.Personality Disorders from the perspective of the Five-factor Model of Personality (Guest Speaker)
11/01/02Zhili HeBioinformatics: From Sequence to Phenotype (Bioinformatics Faculty Candidate)
10/24/02Brien RileyIdentification of genes involved in Drosophila melanogaster geotaxis, a complex behavioral trait. DP Toma, KP White, J Hirsch and RJ Greenspan, Nature Genetics 31: 349-353, 2002
10/23/02Dianjing GuoB-net: a reference biochemical database for metabolomics /Arabidopsis aspartic proteinase gene family identification (Bioinformatics Faculty Candidate)
10/21/02Philip MillerTrends in Bioinformatics (Bioinformatics Faculty Candidate)
10/15/02Andrew PicklesTricking Mx into doing multivariate genetic survival analysis / Molecular genetic developmental models of language development/ disability (Guest Speaker)
10/14/02Thomas KubarychNew Narcissism Scales, A Five-Factor Solution to Personality Disorders and Response to Disconfirming Feedback (PD Candidate)
10/07/02Ming ZhanFrom Genome to Protein Network: Bioinformatics Solutions (Bioinformatics Faculty Candidate)
10/03/02Carol PrescottAre genetic influences on alcoholism risk mediated by individual differences in motivations for drinking?
09/26/02Jack HettemaFear Conditioning and Self-Report Ratings of Fear and Anxiety: Genetic and Environmental Sources of Covariation
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VIPBG Research Seminars 2001-2002

06/18/02Yehuda NeumarkThe genetics of alcoholism (Guest Speaker)
06/06/02Soo RheeModeling comborbidity for substance use and abuse (Guest Speaker)
04/18/02Tim YorkMicroarray analysis of prostate cancer gene expression
04/04/02Federica TozziA Twin Model of Perfectionism
03/28/02Kristen JacobsonThe Role of Puberty in the Development of Antisocial Behavior
03/21/02Mike NealeNew Features and New Developments in Mx
03/21/02David ReissThe role of family social processes in the expression of genetic influence (Guest Speaker) [cancelled]
03/14/02George MoxleySticklebacks and male odors
02/28/02Erica SpottsInterpersonal Relationships and Mental Health: Genetic and Environmental Influences (Guest Speaker)
02/14/02Ken KendlerDimensions of Religiosity and Risk for Adult Psychopathology
02/07/02Jack HettemaA Twin Study of the Genetics of Fear Conditioning
01/24/02Ayman FanousPersonality, Major Depression, and Gender
01/17/02David AllisonLinkage, Association, and Expression Arrays
12/13/01Kevin BolinskeyMMPI Indicators of Schizophrenia: PersonalityAssessment in Pre-and Post-Morbid Participants
12/06/01Jennifer HarrisThe Norwegian Twin Registry (Guest Speaker)
11/29/01Jenae NeiderhiserGenetics and Environmental Influences on relationships among family members: Different patterns across the life span (Guest Speaker)
11/01/01Steve AggenClassification or Measurement: Different Ways of Utilizing Item Response Data: An Application to DSM Major Depression Criteria
10/25/01Amir KhanPersonality and Comorbidity in Psychiatric Disorders
10/18/01Kristen JacobsonGender, cohort, equal environments, and antisocial behavior
10/11/01Hermine MaesWhere there's Smoke....There's Fire
10/04/01Charles AndersonGod and Grub
09/26/01Brien RileyThe Chewbacca Defense
09/14/01Wanqing LiuSerotonin transporter (5-HTT) gene variants associated with schizophrenia? (Post Doc Candidate) [cancelled]
09/13/01Todd WebbFine mapping of a schizophrenia locus on 8p
08/30/01Eva LindholmGenetic Studies of Schizophrenia (Post Doc Candidate)
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VIPBG Research Seminars 2000-2001

07/27/01Wei Zhen YeIdentification of Genes Associated with Type 2 Diabetes in Humans - Study the Candidates Genes (Post Doc Cand.)
07/16/01Kenneth CoggerModern Regression: A Comparative Discussion of Nonlinear Methods (Guest Speaker)
07/13/01Chunhui YuVirtual screening of human BAC's with BM algorithm (Post Doc Candidate)
07/12/01Hongtao FanIdentify potential imprinted gene--bioinformatic and experimental approaches (Post Doc Candidate)
06/05/01Paras MehtaMultilevel Structural Equation Modeling: The Best of Both Worlds
05/31/01Tim YorkAnalysis of gene expression array data
05/24/01Todd WebbBioinformatics
05/11/01Matti HuttunenSchizophrenia - a neurodevelopmental view / Review of Finnish Registers
05/03/01Donna MilesRisk factors for adolescent marijuana use: The Add Health Study
04/26/01Danielle DickThe Finnish Twin Studies: What's New? What's Next?
04/05/01Aymon FanousModifier Loci in Schizophrenia
03/27/01Dawn ThiseltonMolecular Genetic and Genomic Analysis of Two'Monogenic' Retinal Disorders: X-linked retinitis pigmentosa (XLRP) and Autosomal Dominant Optic Atrophy (ADOA)
03/22/01Lindon EavesJinks & Fulker (1970) Comparison of the biometrical genetical, MAVA and classical approaches to the analysis of human behavior II
03/15/01Jack HettemaWhat we know about the genetics of adult anxiety disorders (i.e., and now for something completely different - another meta-analysis)
03/08/01Todd WebbRecent advances in bioinformatics due to the completion of the draft of the Human Genome
03/01/01Kristen JacobsonBehavioral genetic confirmation of a life-course perspective on antisocial behavior: Can we believe the results?
02/15/01Lindon EavesJinks & Fulker (1970) Comparison of the biometrical genetical, MAVA and classical approaches to the analysis of human behavior I
02/01/01Tim YorkCommon disease analysis with MARS
01/25/01Ian JonesPostnatal Depression
01/11/01Scott VranaDeconstructing emotion
12/14/00Hermine MaesGenetic analyses of cardiovascular reactivity and smoking initiation, dependence and cessation
12/07/00Ken KendlerAnalyses in progress on rater bias and mode of acquisition of phobias
12/04/00Nancy CoxIssues and approaches in the identification of genetic variation affecting susceptibility to complex disorders
11/30/00Don MikuleckyComplexity Theory
11/14/00Albert StunkardDeterminants of growth and development of children at high risk for obesity
10/26/00Lenn Murrelle Violent and drug-related behavior in Colombian adolescents: Work in progress
10/20/00Wade PerrettiniGenetic Studies of Psychosis
10/12/00Pat Sullivan Two meta-analyses
10/05/00Judy Silberg Possible genetic mechanisms underlying the development of depression in teenage girls
10/03/00Edwin van den Oord Statistical Modeling with Measured Genotypes
10/02/00Dana HughesIdentification of Predisposition Genes for Major Depression
09/29/00Hans MoisesStrategies in Behavioral Genetics
09/21/00Erik Turkheimer (UVA) SES as a moderator of heritability in the National Collaborative Perinatal Project
09/20/00Martin ReardonOf jellyfish and rubber bands: An inquiry into performance-based identification of high-ability learners
09/18/00Ricky KittlesExploiting the evolutionary history of genes for genetic disease studies
09/14/00Kristen JacobsenAge-related cognitive decline among relatives of schizophrenics and relatives of controls: Differential aging effects
09/11/00Pamela SklarSNPs and neuropsychiatric disorders: Discovery and genotyping
09/07/00Cindy Bulik Intro to Journal Club and Constitutional thinness and resistance to obesity
08/28/00Sam ChenSNP genotyping technologies: Throughput, cost and implication for complex disease studies
08/16/00Brien RileyA study of Schizophrenia in an Ethiopian Population
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VIPBG Research Seminars 99-2000

06/14/00Valerie Knopik Differential Genetic Etiology of Reading-Related Difficulties as a Function of IQ
06/12/00Pavel Kovalenko Seasonal variations in internalizing, externalizing and substance use disorders in youth
05/11/00Carol Prescott Factors Associated with Changes in Alcohol Consumption: Is Marriage a State or Trait?
04/27/00Lindon Eaves Genetic Application of Markov Chain Monte Carlo Methods
04/20/00Steve Aggen The Other Hard Problems: Measuring Behavioral Phenotypes
04/13/00Ken Kendler Eliot Slater's classic monograph, Psychotic and Neurotic Illnesses in Twins (London: Her Majesty's Stationery Office, 1953)
04/06/00Ayman Fanous Quantitative Trait Loci Analysis of Schizophrenia
03/30/00Daijin Ko Regression Diagnostics for Proportional Hazard Models
03/16/00Jack Hettema Generalized Anxiety Disorder in men and women
03/08/00Ian Jones Molecular and genetic approaches to psychiatric disorder
03/02/00Charles MacLean More and more about linkage disequilibrium
02/24/00Hermine Maes Smoking data at VIPBG: Models on Initiation/Dependence/Cessation
02/03/00Mike Neale New software available on the VIPBG network
01/27/00Kristen Jacobson Individual differences in the development of antisocial behavior
12/16/99Chuck Gardner Frequently asked question on Generalized Linear Models
12/09/99Mike Neale Statistical Software on the VIPBG Unix Cluster
12/02/99Ken Kendler An Introduction to The Mind/Body Problem
11/18/99Charles MacLean Trimmed-Haplotype Treatment of the Location Problem
11/04/99Patrick Sullivan Don't Know About You, But I'm Afraid of Epistasis
10/28/99Michael Brown An overview of analytic rotation in exploratory factor analysis
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VIPBG Research Seminars 98-99

05/20/99Ken Kendler Genetics of drug abuse in adult twins
05/06/99Tracy Wade Problems (and Solutions) Encountered in Studying the Genetic Epidemiology of Low Prevalence Disorders
04/22/99Patrick Sullivan Gene Hunting
04/15/99Lindon Eaves Models for parent-offspring interaction
03/25/99Steve Aggen Some alternative models for the biometric structuring of longitudinal data: 4 waves of female-female twin neuroticism data
03/18/99Linda Corey The genetics of epilepsy: an update
03/04/99Emil Coccaro Biological, treatment and family studies of impulsive aggression
02/18/99Seth Roberts Variation in the position of peak LOD score in linkage studies of complex traits
02/11/99Laura Karkowski Examination of gender differences in ilicit substance use and abuse: work in progress
01/28/99Chuck Gardner Likelihoods, Thresholds and Non-Independent Samples: Debunking the conventional wisdom
01/21/99Carol Prescott Evaluating the role of drinking milestones in the etiology of alcohol use disorders
01/14/99Alaattin Erkanli (Duke) Markov Chain Monte Carlo Methods (Guest Speaker)
01/07/99Rory Martin Haplotype Analysis
12/17/98Ken KendlerMarker-to-marker Disequilibrium and phenotypic correlates
12/17/98Charles MacLean Approaches to Haplotype Analysis
12/10/98Mike Neale Issues in Association Analysis: ADH2 and alcohol consumption, and ApoE isoforms and levels
12/03/98Lindon Eaves Genotype x Environment Interaction in Transmission Disequilibrium Test
11/19/98Hermine Maes Genetic Epidemiology: Development of Cardiovascular Risk
10/29/98Kendler/Straub Introduction to Field Methods in the Schizophrenia Study of High-Density Families & Linkage Results
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VIPBG Research Seminars 97-98

05/21/98Debra Foley The Prospective Predictive Priority of Major Depression and Overanxious Disorder
05/14/98Patrick Sullivan Logical Quantitative Traits for a Genome Scan for Nicotine Dependence
04/30/98Charles Gardner Adjusting alpha level for Multiple Test: Theory and Practice
04/23/98Rise Goldstein Familial Aggregation of Delusional Depression
04/09/98David Ross Deficit Syndrome and Eye Tracking Disorder may reflect a Distinct Subtype within Syndrome of Schizophrenia
03/27/98Michael Bailey Genetics of Homosexuality
03/25/98Seth Roberts Neuroticism and Self-esteem as Indices of the Vulnerability to Major Depression in Women
03/13/98J Rappaport Schizophrenia
03/12/98Charles MacLean Haplotype Sharing in Schizophrenia Pedigrees
02/26/98Carol Prescott Using Twin Data to study the Association between Age of Drinking Onset and Alcoholism
02/19/98Richard Straub Applications of DNA Microarray (GeneChip) Technology
02/12/98Kenneth Kendler GE Models of Stressful Life Events
02/05/98Lenn Murrelle The Mid-Atlantic Twin Registry: An Update
01/29/98Patrick Sullivan Genetics of Anorexia Nervosa/ Authorship in the Modern Era
01/08/98Michael Neale Age at Onset and Liability to Disease
12/18/97Charles MacLean Scientific Visualization
12/11/97Steve Aggen Modeling Behavioral Stability, Variability, and Change
12/04/97Charlene Woodard Prevention of Adolescent Substance Abuse
11/06/97Carol Prescott Modeling Selection, Attrition, and Age in Longitudinal Models
10/30/97Hermine Maes Developmental Genetic Analysis of Conduct Disorder
10/09/97Lindon Eaves Revisiting the Environment
10/02/97Rory Martin Haplotype-based Analysis of Linkage Disequilibrium (LD)
09/25/97Charles Gardner Recent Advances in Linear Statistical Modelling
09/4/97Kenneth Kendler Contingent Conditional Model of Psychoactive Substance Use and Dependence
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VIPBG Research Seminars 96-97

06/12/97Patrick Sullivan Latent Class Analysis of Atypical Depressive Symptoms in the National Comorbidity Study
05/29/97Charlene Woodard Genetic Analysis of Child Behavior Checklist among African American Adolescents from Virginia Twin Study
05/15/97Richard Straub Positional Cloning of Genes for Complex Disorders
05/01/97Laura Karkowski Animal Models of Psychopathology
04/17/97Michael Neale Modeling Latent Variable Interactions
03/20/97Carol Prescott Sex Differences in Alcohol Consumption and Alcoholism
02/27/97Judy Silberg A Model for the Emergence of Gender Differences in Adolescent Depression
02/20/97Hermine Maes Genetic and Environmental Factors in Relative Body Weight and Human Adiposity
02/06/97Charles MacLean Estimating and Maximizing Algorithm
01/23/97Charles Gardner Adjusting Statistical Inference for Twin Samples
01/09/97Debra Foley Latent Trait Models and Item Response Theory
12/12/96Lindon Eaves Measuring Environmental Risk in the Presence of Genex Environment Correlation - The Children of Twins: Unravelling the Correlation between the Effects of Genes and the Family Environment on Risk to Disorders of Adolescent Behavior
11/21/96Lenn Murrelle The North Carolina School-Age Twin Study: Methods and Preliminary Findings
Michael Neale Introduction to Mx Graphical Interface
11/7/96Kenneth Kendler Longitudinal Models for Major Depression
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VIPBG Research Seminars 95-96

06/96Carol Prescott Potential Influences of Chorion Type on Twin Study Results
05/30/96Joanne Meyer Power of Affected Sib Pair Sampling for Linkage Analysis
05/02/96Hermine Maes Power to Detect QTL Effect for Correlated Phenotypes
04/18/96Linda Corey The Virginia Twin Registry
03/21/96Michael Neale Hidden Markov Processes and Computing Identity by Descent Probabilities
02/29?/96Carol Prescott Davis et al. (1995) Schiz Bull 21:357-366/ Sokol et al. (1995) Behav Genet 25:457-466
02/01/96Ken Kendler Berrettini et al. (1994) Proc Natl Acad Sci 91:5918-5921/ Ebstein et al. (1996) Nature Genet 12:78-80
Benjamin et al. (1996) Nature Genet 12:81-84/ Stine et al. (1995) Am J Hum Genet 57:1384-1394
01/18/96Charlie MacLean Analysis of Linkage Disequilibrium (Pak Sham & David Curtis: Ann. Hum Genet 59:323-336)
01/04/96Lindon Eaves 2nd session, Kruglyak & Lander
11/30/95Lindon Eaves Kruglyak & Lander
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Seminars on QTL Methods in relation to Obesity, Departments of Psychiatry and Human Genetics, 94

05/4/94Libbie Miller Obesity and Heterogeneity
04/27/94Cindy Shillady Obesity and Mendelian Disorders: a Literature Review
04/20/94Hermine Maes Use of Covariates to Increase Power to Detect QTL Effects
04/13/94Joanne Meyer Developmental Change in Gene Expression for Body Mass Index
?04/06/94Richard Straub Genomic Mismatch Scanning
03/30/94Jeanine Gau Eating Disorders: Anorexia/Bulimia
03/23/94Walter Nance Imprinting
03/09/94Lindon Eaves Sib-Pair Methods/ Identity by Descent
02/23/94Tony O'Neill The Physiology of Obesity
02/16/94Kenneth Kendler Body Mass Index and Depression, Typical and Atypical
02/02/94Arlen Price Genetic Studies on Obesity + Open Forum Discussion on QTL Analysis of Complex Traits
01/26/94Lindon Eaves What do we know about the Measurement, Physiology and Inheritance of Obesity?
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Genetic Seminars on Linkage, Departments of Psychiatry and Human Genetics, 93

11/24/93Charles MacLean Multilocus Linkage
11/17/93Charles MacLean Multipoint Analyses
10/27/93Charles MacLean Interpretation of Linkage Results
10/20/93Charles MacLean Linkage II
09/29/93Charles MacLean Linkage I
09/22/93Charles MacLean Mendel II
09/15/93Charles MacLean Mendel I
09/08/93Charles MacLean Do it yourself linkage seminars
07/28/93Charles MacLean Multipoint Mapping
07/21/93Charles MacLean Ott J, Analysis of Human Linkage, Variability of the Recombination Fraction
07/14/93Charles MacLean Ott J, Analysis of Human Linkage, Numerical and Computerized Methods
07/07/93Charles MacLean Ott J, Analysis of Human Linkage, Multipoint Linkage Analysis
06/30/93Charles MacLean Ott J, Analysis of Human Linkage, The Informativeness of Family Data
06/16/93Charles MacLean Ott J, Analysis of Human Linkage, Methods of Linkage Analysis
06/09/93Charles MacLean Ott J, Analysis of Human Linkage, Genes and Genetic Polymorphisms/ Aspects of Statistical Inference
06/02/93Charles MacLean Linkage analysis made easy
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Seminars on Ascertainment and the Analysis of Family Data, Departments of Psychiatry and Human Genetics, 93

05/13/93Jennifer Reynolds Human Gene Mapping: Applications to Neurofibromatosis and Waardenburg Syndrome (Dissertation Defense)
05/05/93Carol Prescott DC Rao & R Wette (1987) Non-random sampling in genetic epidemiology: Maximum likelihood methods for multifactorial analysis of quantitative data ascertained through truncation. Gen et Epidemiol, 4:357-376
04/26/93David B. Allison Issues in the Genetics of Obesity (Special Seminar)
04/14/93Michael C. Neale RJA Little & DB Rubin (1987) Statistical analysis with missing data. New York, Wiley & Son
04/07/93Charles MacLean The consequences of ascertaining high density pedigrees for linkage analysis
03/24/93K.S. Kendler K.S.Kendler, L.J. Eaves: The Estimation of Probandwise Concordance in Twins: The Effect of Unequal Ascertainment
03/17/93Ellen Walters DA Greenberg (1986) The effect of proband designation on segregation analysis. Am J Hum Genet, 39,329-339
03/10/93Lindon Eaves WJ Ewens & NCE Shute (1986) A resolution of the ascertainment sampling problem: I Theory. Theo Pop Biol 30:388-412/ NCE Shute & WJ Ewens (1988) A resolution of the ascertainment sampling problem: II Generalizations and numerical results. Am J Hum Genet 43:374-386
02/24/93Scott Diehl NJ Schork: Detection of Genetic Heterogeneity for Complex Quantitative Phenotypes
Extended Pedigree Patterned Covariance Matrix Mixed Models for Quantitative Phenotype Analysis
02/10/93Charles MacLean C Cannings & EA Thompson (1977) Ascertainment in the sequential sampling of pedigrees. Clin Genet 12:208-212
02/03/93Mary Marazita NE Morton (1959) Genetic tests under incomplete ascertainment. Am J Hum Genet 11:1-16
NE Morton & MP Mi (1968) Multiplex families with two or more probands. Am J Hum Genet 20:361-367
01/27/93Michael Neale AC Aitken (1934) Note on selection from a multivariate normal population. Proc Edin Math Soc 4:106-110
01/13/93Pak Sham RA Fisher (1934) The effect of methods of ascertainment upon the estimation of frequencies. Ann Eugen 6:13-25
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Quantitative Genetics Research Seminar Departments of Psychiatry and Human Genetics, 92

12/18/92John R. Nesselroade Intraindividual Variability: Selected Methods, Findings, and Implications
12/15/92Joanne Meyer Genetic Analyses of Drug Abuse in the Vietnam Era Twin Study
12/11/92Deborah Dawson Extended HLA Profile of an Inbred Caucasian Isolate
12/04/92Ina Hoeschele Estimation of Variance Components in Models for Family Resemblance including Dominance and Inbreeding
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Hard Problems Seminars 2002-2003

05/01/03Lindon EavesAn introduction to BUGS
03/13/03Ben Neale/EdwinHaplotype Block Controversy
02/27/03Daijin KoMicroarry Dimension Reduction
02/13/03Edwin van den OordFalse positives: How to keep the baby while tossing out the bath water
12/12/02Daijin KoMicroarrays and Data Mining
12/05/02Daijin KoAn Idiot's Guide to the False Discovery Rate
11/21/02Carol PrescottIRB do's and don'ts
11/14/02Tim York Microarrays and Prostate Cancer
11/07/02Edwin van den OordFalse Discovery Rates in Linkage
10/31/02Ben NealeGenomewide Scan for Nicotine Dependence Study
10/17/02Andrew PicklesGenetic Analysis of Developmental Processes: Aquiring language and passing developmental milestones
10/10/02Mike NealeUsing Mx for Linkage Analysis
09/26/02George MoxleyAllelic Variation in Human Gene Expression Cite (Science 08/16/2002, page 1143)
09/19/02Ken Kendler eaProposed program project grant on "Genetics of Nicotine Dependence and Acute Response"
08/01/02Pat SullivanWhat I did in Sweden? Collaborative Projects
07/25/02Jonathan KuhnErrors of Omission
07/18/02George MoxleyStructure of Haplotype Blocks in the Human Genome (Science 21/06/2002, p 2225)
07/11/02Chuck GardnerSome useful tips on statistical interactions
06/27/02Meike BartelsFitting longitudinal rater models to CBCL ratings of problem behaviors
06/20/02Todd WebbAn update in Bioinformatics Tools
06/13/02Lindon EavesFractals & Freedom: getting from DNA to a person
06/13/02Carol PrescottWhat you had damn well better know about the ethics of family history research
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Hard Problems Seminars 2001-2002

03/14/02Patrick SullivanACE modeling
03/07/02Patrick SullivanPlomin et al (Behav Genet 2001, 31:497)
03/07/02Ken KendlerTurri et al (Current Biology 2001, 11:725-34)
02/28/02Erica SpottsInterpersonal Relationships and Mental Health: Genetic and Environmental Influences
02/14/02Patrick SullivanTalking Back to Twin Critics
01/31/02Sam ChenGenotyping II
01/24/02Walter NanceGenetic Studies of the Most Important Event in Human Evolution
01/17/02David AllisonStatistical Methods for Micro-array Analysis
12/13/01Sam ChenGenotyping I
10/31/01Brien Riley Molecular Genetics of Autism
10/18/01Ken KendlerLinkage Disequilibrium and Recombination
10/11/01Patrick SullivanUnivariate Twin Modeling of Discrete Traits: Are We Doing It Wrong?"
10/04/01Michael MilesFunctional Genomics in the Neurobiology of Drug Abuse
09/27/01Chuck GardnerMultiple Imputation - why and how?
09/20/01Ken KendlerTwo recent Nature articles which appear to have nailed a gene for a complex trait
09/13/01Ted Reichborn/Espen RoysambNorwegian Research
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Hard Problems Seminars 2000-2001

06/21/01Sam ChenUse of Biological Haplotypes in Gene-finding
06/14/01Panos FatourosThe new MCV MRI Facility
06/07/01Patrick SullivanSearch for new Faculty
05/31/01Tim YorkAnalysis of Gene Expression Array data
05/24/01Todd WebbBioinformatics
05/17/01Patrick SullivanAre Genotypes Enough?
05/10/01Patrick SullivanNicotine Research
05/03/01Carol PrescottGenotyping and Analysis of the Irish Alcohol sib pairs
04/12/01Mike Neale eaMeasurement and Methodology: How Long is a Piece of Psychopathology?
03/22/01Brien RileyLatest claim for a "schizophrenia gene" from Lesch' group in Germany
03/15/01Ian JonesBias caused (or not) by Population Stratification in Case-control Association Studies using Genetic Markers
03/08/01Patrick SullivanMad Cows & Madmen: Candidates Genes for Schizophrenia
03/01/01Patrick SullivanDiscovery Science: Gene Expression in Chronic Fatigue Syndrome
02/15/01Patrick SullivanWhat we need to do to (a) keep heads above water and (b) stay ahead of the wave
02/08/01Patrick SullivanThreats to the intellectual underpinninngs of our work II
02/01/01Patrick SullivanThreats to the intellectual underpinninngs of our work I
01/18/01Ken KendlerThoughts on the Fly (Drosophila)
12/21/00Lindon EavesGenetic Analysis in Bugs
11/30/00Lindon EavesIntroduction to BUGS (Bayesian Inference Using Gibbs Sampler)
10/26/00Patrick SullivanVIPBG Research Directions
10/12/00Ken KendlerShow & Tell
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