Edwin J.C.G. van den Oord, Ph.D.
Professor
Director Center for Biomarker Research and Personalized Medicine
Virginia
Institute for Psychiatric and Behavioral Genetics
Medical College of Virginia of Virginia Commonwealth University
P.O. Box 980533, Richmond VA 23298-0533, USA
Phone (804) 379 2091/ (804) 828 8350
Fax (804) 828 8359
e-mail: ejvandenoord@vcu.edu
For express mail/FEDEX
Smith Building, Room 450
410 North 12th Street
Richmond VA 23298, USA
Downloads (zipped) and links:
QQ-plots for article "Genome-wide Pharmacogenomic Analysis of Response to Treatment with Antipsychotics" by Joseph L. McClay, Daniel E. Adkins, Scott Stroup, Diana O. Perkins, Jeffrey A. Lieberman, Patrick F. Sullivan, Edwin J.C.G. van den Oord
Mplus and Mx scripts for the paper "The use of Finite Mixture Models to Handle Drug Response Heterogeneity in Pharmacogenetic Studies" by Timothy P. York, Cristina Vargas-Irwin, and Edwin J. C. G. van den Oord.
Supplemental material and all GWAS p-values related to the paper Edwin J.C.G. van den Oord, Po-Hsiu Kuo, Annette M. Hartmann, B. Todd Webb, Hans-Jürgen Möller, John M. Hettema, Ina Giegling, József Bukszár, and Dan Rujescu (2008). "Genomewide Association analysis followed by a replication study implicates a novel neuroticism gene". Archives of General Psychiatry (Sept).
Supplemental material for the paper: Genetics and Diagnostic Refinement by Van den Oord, E. J. C. G., Joseph L McClay, Timothy P. York, Lenn Murrelle, and Jaime R. Robles (2007) in Behavior Genetics, 37, 535-545.
Supplemental material and Splus/R code used in the article by Bukszár, J. & Van den Oord, E. J. C. G (2006). Optimization of two-stage genetic case-control designs where data are combined using an accurate and efficient approximation for Pearson’s statistic. Biometrics, 62, 1132-1137.
Forrester diagrams of model parts, Stella models, picture showing full model, and S-PLUS/R scripts for the paper Joseph L McClay and Edwin JCG van den Oord (2006). Variance component analysis of polymorphic metabolic systems. Journal of Theoretical Biology, 240, 149-159.
Supplemental material for the paper by Timothy P. York, Lindon J. Eaves, & Edwin J. C. G. van den Oord (2006). Multivariate adaptive regression splines: A powerful method for detecting disease-risk relationship differences among subgroups. Statistics in Medicine, 25, 1355-1367.
Supplemental figures and tables + zipped Splus/R code used to calculate power for 2×2 and 2×3 tables in the MS: Bukszár, J. & Van den Oord, E. J. C. G. (2005). Accurate and efficient power calculations for 2×m tables in unmatched case-control designs. Statistics in Medicine, 24, 2632-2646.
Supplemental material for the paper: Van den Oord, E. J. C. G. (2005). Controlling false discoveries in candidate gene studies. Molecular Psychiatry, 10, 230 -231
Link to the program lga972 and its manual. The program is discussed in the paper: Robles, J.R. & van den Oord, E.J.C.G. (2004). lga972: A cross-platform application for optimizing LD studies using a genetic algorithm. Bioinformatics, 20, 3244-3245.
Details of the
calculations performed in the MS: Van den Oord,
E. J. C. G., & Sullivan, P. F. (2003).
lga972
now replaces code used for the calculations performed in the article:
Van den
Oord, E. J. C. G., &
Sullivan, P. F.
Program Assign plus documentation for FP-TDI SNP genotype scoring in Mplus as discussed in the article: Van den Oord, E. J. C. G., Jiang, Y., Riley, B. P., Kendler, K. S., & Chen, X. (2003). FP-TDI SNP Scoring by manual and statistical procedures: A study of error rates and types. BioTechniques, 34, 610-624.
Program MxScript plus documentation discussed in the paper: Van den Oord, E. J. C. G., & Snieder, H. (2002). Including measured genotypes in statistical models to study the interplay of multiple factors affecting complex traits. Behavior Genetics, 32, 1-19.
Mx scripts and Mplus scripts used in the article: Van den Oord, E. J. C. G. (2000). The use of mixture models to perform quantitative tests for linkage disequilibrium, maternal effects, and parent-of-origin effects with incomplete subject-parent triads. Behavior Genetics, 30, 335-343.
LEM scripts plus documentation as discussed in paper: Van den Oord, E. J. C. G. & Vermunt, J. K. (2000). Testing for linkage disequilibrium, maternal effects, and imprinting with (in)complete case-parent triads, by use of the computer program LEM. American Journal of Human Genetics, 66, 335-338.
Links to R, Mplus, Mx, and LEM
Last updated on August 14, 2008